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Limonin, nomilin, and nomilinic acid are the predominant limonoids
in citrus fruits. These limonoids exist in citrus fruit primarily in
the form of glucosides. Unlike the aglycones, the limonoid glucosides
(LG) are not bitter. Recent studies in Dr. Miller's laboratory at Baylor
College of Dentistry have shown that limonoids and their corresponding glucosides
are inhibitors of chemical carcinogenesis. Since the concentration of
LG in orange juice and grapefruit juice is 320 and 190 ppm, respectively,
the regular consumption of these products exposes the consumer to relatively
high concentrations of these anticancer agents. Efforts to increase
exposure to LG should increase the potential health benefits. Recently,
a company in Japan formulated a test product, designated LG1000, in which
the concentration of LG in a mandarin orange juice was increased from 200
to 1,000 ppm. |
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